Consumer medicine information

ZANTAC® effervescent tablets

ranitidine (as hydrochloride)

Consumer Medicine Information

About your Zantac Effervescent tablets

Read all of this leaflet carefully before you take your medicine.

This leaflet does not have the complete information available about your medicine. If you have any questions about your medicine, you should ask your doctor or pharmacist (also known as chemist).

All medicines have some risks. Sometimes new risks are found even when a medicine has been used for many years.

If there is anything you do not understand, ask your doctor or pharmacist. If you want more information, ask your doctor or pharmacist.

What is in my Zantac?

The medicine in your Zantac effervescent tablets is called ranitidine (as hydrochloride). This belongs to a group of medicines called H2-antagonists.

What does my Zantac do?

Zantac is mostly used to:

  • treat stomach and duodenal ulcer disease (also known as peptic ulcer),
  • stop these ulcers from coming back,
  • treat reflux oesophagitis (also known as reflux).

These problems are caused, in part, by too much acid in the stomach. This can lead to pain such as heartburn. Zantac works by reducing the amount of acid in the stomach. This reduces the pain and also allows the ulcer and reflux to heal.

Zantac is also used to treat:

  • Zollinger-Ellison disease,
  • scleroderma oesophagitis.

Before you take it

Do not take if:

You must not take Zantac if:

  • you have ever had an allergic (hypersensitive) reaction to ranitidine or any of the ingredients listed towards the end of this leaflet.
  • the expiry date (EXP) printed on the pack has passed.
  • the packaging is torn or shows signs of tampering.

Tell your doctor if:

You must tell your doctor if:

  • you are allergic to foods, dyes, preservatives or any other medicines.
  • you have ever had an allergic (hypersensitive) reaction to ranitidine or any of the ingredients listed towards the end of this leaflet.
  • you are allergic to any medicine,
  • you have stomach cancer.
  • you have kidney disease,
  • you have had stomach ulcers before and you are taking Non-Steroidal Anti-Inflammatory (NSAID) medicines.
  • you have a disease known as acute porphyria,
  • you are on a restricted sodium intake,
  • you have phenylketonuria.
  • you are over 65 years of age.
  • you have lung disease.
  • you are diabetic.
  • you have any problems with your immune system.
  • you have had to stop taking this or any another medicine for your ulcer or reflux,

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, have taken any recently, or if you start new ones. This includes herbal medicines and any other medicines you have bought without a prescription.

Zantac can affect the way some other medicines work. Also other medicines can affect the way Zantac works.

In particular tell your doctor or pharmacist if you are taking any of the following medicines:

  • warfarin, used to prevent blood clots
  • triazolam and midazolam, used as sedatives
  • ketoconazole, an anti-fungal
  • atazanavir and delaviridine, used to treat HIV
  • glipizide, used for diabetics
  • gefitinib, used in the treatment of cancer
  • Non-Steroidal Anti- Inflammatory (NSAID) medicines, for pain and inflammation
  • procainamide or n-acetylprocainamide, used to treat heart problems
  • sucralfate used to treat ulcers

What if I am pregnant or breast feeding?

Tell your doctor if you are pregnant, likely to get pregnant or are breast feeding. Your doctor will tell you if you should take this medicine.

How do I take it

  • The dosage depends on the disease that you are suffering from. Your doctor or pharmacist will usually tell you how many Zantac effervescent tablets to take and how often to take them. You will also find this information on the label of your medicine.
  • The normal adult dosage is 150 to 300 milligrams per day, taken as one 150 mg effervescent tablet once or twice a day, or two 150 mg effervescent tablets taken at bedtime. Your doctor may prescribe a different dosage.
  • Do not take extra effervescent tablets. Do not take the effervescent tablets more often than you have been told.
  • It does not matter whether you take the effervescent tablets before or after food.
  • Zantac effervescent tablets should be placed in at least half a glass of water (about 75 mL). Allow the tablet to dissolve before you drink the liquid. Swirl the glass if necessary.
  • Your pain or other symptoms may take a few days to go away.
  • Take all the effervescent tablets your doctor has prescribed for you, even if you feel better.
  • Even when you have completed your effervescent tablets, your doctor may decide to continue your treatment with Zantac, possibly at a different dosage, in order to prevent the problem coming back again.

Use in Children:

Zantac has not been studied fully in children. Do not give to children unless you have discussed the risks and benefits involved with your doctor.

What should I do if I miss my dose?

If you forget to take your Zantac, take another as soon as possible unless it is nearly time for your next dose. Do not take a double dose to make up for the missed one.

Side effects

Like other medicines, Zantac may cause some side-effects. Most of the side-effects will be minor and temporary, but some may be serious. Your doctor will be able to answer any questions you may have.

Tell your doctor straight away and do not take any more Zantac if you have:

  • an allergic reaction, the signs may include:
    – skin reactions such as rash (red spots), itching, skin lumps or hives,
    – swelling of the eyelids, face, lips, tongue or other parts of the body,
    – shortness of breath, trouble breathing, wheezing, chest pain or tightness,
    – unexplained fever and feeling faint, especially when standing up.
  • severe stomach pain or a change in the type of pain,
  • yellow colouring of the skin or eyes (jaundice),
  • confusion,
  • general illness associated with weight loss,
  • fever,
  • irregular heart beat (including unusually fast or slow heart beats),
  • change to heart beat.

If you get any of the following side effects after taking Zantac tell your doctor, but there is no immediate reason to stop taking the effervescent tablets unless you are concerned:

  • headache,
  • joint or muscle pains,
  • dizziness,
  • depression,
  • constipation.
  • feeling sick (nausea) or vomiting,
  • diarrhoea,
  • breast tenderness and/or breast enlargement,
  • breast discharge,
  • change in liver function tests.

If you notice any symptoms that concern you or if the effervescent tablets cause any other side effects, tell your doctor or pharmacist.

If you have taken all the effervescent tablets and still do not feel better tell your doctor as soon as possible.

Other side effects not listed above may also occur in some people.


Immediately telephone your doctor or Poisons Information Centre (telephone 131126) for advice, if you think you or anyone else may have taken too much Zantac, even if there are no signs of discomfort or poisoning. If you are not sure what to do, contact your doctor or pharmacist.


  • Keep your Zantac effervescent tablets away from heat (below 25°C). For example, you should not leave them in the car on hot days.
  • Please keep your Zantac effervescent tablets in a place where children cannot reach them.
  • You will find an “expiry” (or use by) date printed on the manufacturer’s label of the pack. Do not use the effervescent tablets after this date. Do not use the effervescent tablets if they are discoloured.
  • Keep your Zantac effervescent tablets away from moisture. Leave the effervescent tablets in the pack until you are ready to use them.

Product description

What Zantac 150 mg effervescent tablets look like:

Zantac 150 mg effervescent tablets are a white to pale yellow, bevelled tablets debossed “GS LHK” on one side and flat on the other.


Each Zantac Effervescent tablet contains 150 mg of ranitidine (as hydrochloride) and are available in packs of 30 tablets in polypropylene tubes.

Zantac 150 mg effervescent tablets also contain the inactive ingredients:
Aspartame, Grapefruit flavour 18C222, monosodium dihydrogen citrate, Orange flavour No. 6, povidone, sodium benzoate and sodium bicarbonate.

  • PHENYLKETONURICS: Contains Phenylalanine.
  • Each tablet contains 328 mg of sodium.
  • Zantac effervescent tablets are free from gluten.

Can I let someone else use my Zantac?

Never give this medicine to someone else. The medicine is only for you. It may harm other people even if they seem to have the same symptoms that you have.


Aspen Pharmacare Australia Pty Ltd
34-36 Chandos Street
St Leonards NSW 2065

Zantac® is a registered trade mark of Aspen Global Incorporated.

Do not throw this leaflet away. You may need to read it again.

This leaflet was revised in September 2017.

Zantac Effervescent tablets 150 mg – AUST R 45993

© 2012 Aspen Global Incorporated.

Published by MIMS November 2017