Consumer medicine information

XYCILAN™ 250 & 500

Amoxycillin (as trihydrate) 250 mg and 500 mg capsules

Consumer Medicine Information

What is in this leaflet

Please read this leaflet carefully before you take XYCILAN.

This leaflet answers some common questions about XYCILAN. It does not contain all of the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Sometimes new risks are found even when a medicine has been used for many years. Your doctor has weighed the expected benefits of you taking XYCILAN against the risks this medicine could have for you.

Take XYCILAN as instructed. If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

What XYCILAN is used for

XYCILAN contains a penicillin called amoxycillin as the active ingredient.

XYCILAN belongs to a group of medicines called penicillins.

XYCILAN is used to treat a range of infections caused by bacteria. These may be infections of the chest (pneumonia), tonsils (tonsillitis), sinuses (sinusitis), urinary and genital tract, skin and fleshy tissues.

XYCILAN works by killing the bacteria that cause these infections. XYCILAN can also be used to prevent infection.

Your doctor may have prescribed XYCILAN for another reason.

There is no evidence that XYCILAN is addictive.

Before you take XYCILAN

When you must not take it:

  • you are allergic to penicillin or similar types of antibiotics such as cephalosporins. If you have ever had an allergic reaction (such as a rash) when taking an antibiotic you should tell your doctor before you take XYCILAN;
  • you have ever had an allergic reaction to amoxycillin or any of the ingredients listed towards the end of this leaflet. (See “Ingredients”);
  • the expiry date printed on the pack has passed; or
  • the packaging is torn or shows signs of tampering.

Tell your doctor if:

  • you are allergic to foods, dyes, preservatives or any other medicines;
  • you have ever had an allergic reaction (such as a rash) to any antibiotics in the past;
  • you have glandular fever (mononucleosis) or a blood disorder;
  • you are pregnant or think you may be pregnant or are breast feeding. XYCILAN may be used during pregnancy (Australian Use in Pregnancy Category A). XYCILAN can pass to your baby from breast milk;
  • you have liver or kidney problems. The dosage of XYCILAN may need to be changed or you may need to be given an alternative medicine; and/or
  • you are taking any other medicines, including medicines you buy without a prescription. In particular tell your doctor if you are taking any of the following:
    – medicines used to treat gout e.g. probenecid or allopurinol;
    – the contraceptive pill. As with other antibiotics, you may need to use extra birth control methods e.g. condoms;
    – other antibiotics. These may interfere with the actions of XYCILAN; or
    – Anticoagulants (used to prevent blood clots) such as warfarin.

Some medicines may affect the way other medicines work. Your doctor or pharmacist will be able to tell you which medicines are safe to take with XYCILAN.

If you have not told your doctor about any of these things, tell them before you take any XYCILAN.

How to take it

Follow your doctor’s instructions about how and when to take XYCILAN. Your doctor will advise how many doses are needed each day, and for how long you will need to take XYCILAN.

Please read the direction label carefully. If you have any concerns about how to take XYCILAN, talk to your doctor or pharmacist.

How much XYCILAN to take

Take XYCILAN as directed by your doctor or pharmacist.

The usual dose of XYCILAN is one dose taken three times a day.

How to take XYCILAN

Swallow XYCILAN 250 mg and 500 mg capsules whole with a glass of water.

Space the doses as evenly as possible throughout the day. For example, if you are taking XYCILAN three times a day, take a dose about every eight hours.

XYCILAN can be taken with or without food. The effects of XYCILAN are not changed by food.

How long to take XYCILAN

Keep taking XYCILAN until the course is finished or for as long as your doctor tells you.

Do not stop taking XYCILAN just because you feel better as the infection can return.

Do not stop taking XYCILAN, or change the dose without first checking with your doctor.

If you forget to take it

If you forget to take a dose of XYCILAN, take it as soon as you remember. Then go back to taking it as directed by your doctor.

Do not take a double dose to make up for the dose that you have missed. Do not take two doses within an hour or so of each other. Taking more than the prescribed dose can increase the chance of unwanted side effects.

If you take too much (overdose)

If you (or someone else) has taken a large amount of XYCILAN all at once, give plenty of water to drink and immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, if you think you or anyone else may have taken too much XYCILAN, even if there are no signs of discomfort or poisoning.

If you are not sure what to do, contact your doctor, pharmacist or nearest hospital.

While you are taking it

Things you must do

Tell your doctor if, for any reason, you have not taken your medicine exactly as directed.

Otherwise, your doctor may think that it was not working as it should and change your treatment unnecessarily.

Tell your doctor or pharmacist you are taking XYCILAN before starting any other prescribed medicine. Some medicines may affect the way other medicines work.

If you develop itching, swelling or a skin rash when you are taking XYCILAN, do not take any more XYCILAN and tell your doctor at once.

If you develop severe diarrhoea when taking XYCILAN tell your doctor as soon as possible. Do not take any medication to stop the diarrhoea.

Things you must not do

Do not give this medicine to anyone else, even if their symptoms seem similar to yours.

Do not use XYCILAN to treat any other complaints unless your doctor says to.

Things to be careful of

Be careful driving or operating machinery until you know how XYCILAN affects you.

Side effects

Check with your doctor as soon as possible if you think you are experiencing any side effects or allergic reactions due to taking XYCILAN, even if the problem is not listed below.

Like other medicines, XYCILAN can cause some side-effects. If they occur, they are most likely to be minor and temporary. However, some may be serious and need medical attention.


  • Tell your doctor if you notice any of the following that are troublesome or ongoing:
    – diarrhoea (several loose bowel movements per day), indigestion, feeling sick or being sick;
    – soreness of the mouth or tongue; or
    – overgrowth of yeast infections (thrush).


  • Tell your doctor immediately if you notice any of the following:
    – itching, rash;
    – unusual bleeding or bruising;
    – yellowing of the skin or eyes;
    – dark urine or pale stools;
    – difficulty or pain on passing urine; or
    – severe diarrhoea.
  • Stop taking XYCILAN and contact your doctor or go to the emergency department of your nearest hospital if any of the following happens:
    – Wheezing, swelling of the lips/mouth, difficulty in breathing, hay fever, lumpy rash (hives) or fainting. These could be symptoms of an allergic reaction.

Remember you should tell your doctor or pharmacist as soon as possible if any of these, or any other unusual events or problems occur during or after treatment with XYCILAN.

This is not a complete list of all possible side-effects. Others may occur in some people and there may be some side-effects not yet known.

Tell your doctor or pharmacist if you notice any side effects from your medicine which are not mentioned here.

Do not be alarmed by this list of possible side-effects. You may not experience any of them.

After taking it


Keep your medication in the pack until it is time to take them.

Keep this medicine where children cannot reach it, such as in a locked cupboard.

Keep the pack in a cool dry place where the temperature stays below 25°C. Do not leave it in the car on a hot day. Do not store medicine in the bathroom or near a sink. Heat and dampness can destroy some medicines.

Return any unused or expired medicine to your pharmacist.

Product description

What XYCILAN looks like

XYCILAN 250 & 500 (250 & 500 mg amoxycillin as trihydrate) are presented in blister packs of 20 capsules.

XYCILAN 250 (AUST R 185795)
Maroon/yellow size ‘1’ hard gelatin capsule filled with white to off-white granular powder and imprinted with ‘A’ on maroon cap and ‘85’ on yellow body with black ink.

XYCILAN 500 (AUST R 185797)
Maroon/yellow size ‘0EL’ hard gelatin capsule filled with white to off-white granular powder and imprinted with ‘A’ on maroon cap and ‘86’ on yellow body with black ink.


Active Ingredient:

Amoxycillin (as trihydrate).

Each capsule contains 250 mg or 500 mg of amoxycillin (as trihydrate).

Other Ingredients:

  • Microcrystalline cellulose
  • Magnesium stearate

The capsule shells also contain gelatin, carmoisine (E122), iron oxide yellow (E172), patent blue V (E131), titanium dioxide (E171) and sodium lauryl sulfate.

Sponsor/Marketing Authorisation Holder

Aurobindo Pharma Australia Pty Ltd
6 Eastern Road
South Melbourne
Victoria 3205

Distributed by Eris Pharmaceuticals (Australia) Pty Ltd

Toll free telephone (Australia): 1800 233 588

This leaflet was prepared in August 2015

Version 2.0

Published by MIMS July 2017