Ceftazidime-AFT

Ceftazidime-AFT

Active ingredient(s): Ceftazidime (as pentahydrate)

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Consumer Medicine Information (CMI)

This leaflet provides important information about using Ceftazidime-AFT. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using Ceftazidime-AFT.

Where to find information in this leaflet:

1. Why am I given Ceftazidime-AFT?
2. What should I know before I am given Ceftazidime-AFT?
3. What if I am taking other medicines?
4. How is Ceftazidime-AFT Given?
5. What should I know while I am given Ceftazidime-AFT?
6. Are there any side effects?
7. Product details

1. Why am I given Ceftazidime-AFT?

Ceftazidime-AFT contains the active ingredient Ceftazidime (as pentahydrate). Ceftazidime-AFT belongs to a group of medicines called cephalosporins.

Ceftazidime-AFT is used to treat a wide range of infections caused by bacteria. These infections may affect the chest (bronchitis or pneumonia), ears, nose, throat, bladder and urinary tract, skin and soft tissue, stomach or bones.

Ceftazidime-AFT works by killing the bacteria that cause these infections.

Your doctor may have prescribed Ceftazidime-AFT for another reason.

2. What should I know before I am given Ceftazidime-AFT?

Warnings

You should not be given Ceftazidime-AFT if:

• you are allergic to ceftazidime (as pentahydrate), cephalosporins, penicillins or any of the ingredients listed at the end of this leaflet. Always check the ingredients to make sure you can use this medicine,
• the expiry date (EXP) printed on the pack has passed,
• the packaging is torn or shows signs of tampering.

Check with your doctor if you:

• have any other medical conditions,
• take any medicines for any other condition including medicines you buy without a prescription,
• are allergic to foods, dyes, preservatives or any other medicines (in particular cephalosporins, penicillins, chloramphenicol or lignocaine),
• are taking oral contraceptives (birth control pills),
• have had to stop taking another medicine for your infection,
• have kidney or liver problems,
• have had stomach or bowel illness (for example, colitis),
• test your urine for sugar. While on Ceftazidime-AFT, you need to have your blood tested for a blood transfusion,
• are breastfeeding, pregnant or trying to become pregnant.

During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. See additional information under Section 6. Are there any side effects?

Pregnancy and breastfeeding

Check with your doctor if you are pregnant or intend to become pregnant.

Talk to your doctor if you are breastfeeding or intend to breastfeed.

Ceftazidime-AFT is not recommended for use during pregnancy and breastfeeding. If there is a need to consider Ceftazidime-AFT during pregnancy or breastfeeding, your doctor will discuss with you the benefits and risks of using it.

3. What if I am taking other medicines?

Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may interfere with Ceftazidime-AFT. These include:

• chloramphenicol, an antibiotic used to treat bacterial infections,
• diuretics, a medicine which helps to reduce the amount of excess fluid in the body by increasing the amount of urine produced,
• aminoglycosides, an antibiotic used to treat serious bacterial infections.

These medicines may be affected by Ceftazidime-AFT or may affect how well it works. You may need different amounts of your medicine, or you may need to take different medicines.

Talk to your doctor about the need for an additional method of contraception while being given Ceftazidime-AFT.

Some antibiotics may decrease the effectiveness of some birth control pills, although this has not been shown with Ceftazidime-AFT

Your doctor or pharmacist may have more information on medicines to be careful with or avoid while being given Ceftazidime-AFT.

4. How is Ceftazidime-AFT given?

How much is given

• Ceftazidime-AFT will be administered as directed under the supervision of a doctor or nurse. You will not be expected to give yourself this medication.

When Ceftazidime-AFT is given

• Ceftazidime-AFT will be injected deep into muscle tissue or into a vein. When it is injected into a vein it may be given directly or through a ‘drip’.
• DO NOT try to use the injection on your own unless your doctor has told you to do so and given you complete instructions.
• Ceftazidime-AFT should be administered for as long as recommended by your doctor.

If too much Ceftazidime-AFT is given

As Ceftazidime-AFT is given under medical supervision, it is very unlikely that you will receive too much.

However, if you experience severe side effects after being given ceftazidime, you should immediately:

• phone the Poisons Information Centre
  (by calling 13 11 26), or
• contact your doctor, or
• go to the Emergency Department at your nearest hospital.

You should do this even if there are no signs of discomfort or poisoning.

Symptoms of a ceftazidime overdose may include the side effects listed below in section 6 ‘Are there any side effects?’ but are usually of a more severe nature.

You may need urgent medical attention.

Ask your doctor if you have any concerns.

5. What should I know while I am given Ceftazidime-AFT?

Things you should do

• Tell your doctor if you are allergic to cephalosporins, penicillins or other antibiotics.
• Tell your doctor if you have kidney or liver problems.
• Tell your doctor that you are being given Ceftazidime-AFT before taking any other prescribed medicine or performing any urine or blood tests. Some medicines may affect the way other medicines work.

Things you should not do

• Do not give this medicine to anyone else, even if their symptoms seem similar to yours.
• Do not use Ceftazidime-AFT to treat any other complaints unless your doctor says to.

Driving or using machines

Be careful before you drive or use any machines or tools until you know how Ceftazidime-AFT affects you.

Looking after your medicine

Ceftazidime-AFT will be stored in the pharmacy or on the ward. The powder for injection is kept in a cool, dry place, protected from light, where the temperature stays below 25°C.

6. Are there any side effects?

All medicines can have side effects. If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention.

See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects. Do not be alarmed by this list of possible side-effects. You may not experience any of them.

Less serious side effects

Less serious side effects	What to do
Body as a whole: pain or flaking skin where you had the injection headache dizziness numbness or tingling bad taste in mouth sore mouth or tongue vaginal discharge, genital itching. Gastrointestinal related: stomach pain nausea (feeling of sickness) or vomiting	Speak to your doctor if you have any of these less serious side effects and they worry you.

Serious side effects

Serious side effects

What to do

Allergic reaction related: skin trouble such as a rash, red spots, itching, skin lumps, hives, blisters or peeling swelling of the eyelids, face or lips difficulty breathing Wheezing, swelling of the lips/mouth, difficulty in breathing, hayfever, lumpy rash (hives) or fainting. These could be symptoms of an allergic reaction. Body as a whole: diarrhoea (even several weeks after your Ceftazidime-AFT treatment) high temperature (fever) bruising or bleeding shaking or muscle twitches Reduced ability to think clearly or concentrate, memory loss, drowsiness, seizures, muscle twitches and personality change. These symptoms may be related to a condition called encephalopathy.

Call your doctor straight away, or go straight to the Emergency Department at your nearest hospital if you notice any of these serious side effects.

Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.

Other side effects not listed here may occur in some people.

Reporting side effects

After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems. By reporting side effects, you can help provide more information on the safety of this medicine.

Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.

7. Product details

This medicine is only available with a doctor’s prescription.

What Ceftazidime-AFT contains

Active ingredient (main ingredient)	Ceftazidime (as pentahydrate)
Other ingredients (inactive ingredients)	Sodium carbonate

Do not take this medicine if you are allergic to any of these ingredients.

What Ceftazidime-AFT looks like

Ceftazidime-AFT looks like a white or almost white crystalline powder. The powder is reconstituted with sterile water prior to injection. Once made up the solution should be a clear and light yellow to amber colour (Aust R 277679, 277680).

Who distributes Ceftazidime-AFT

AFT Pharmaceuticals Pty Ltd
113 Wicks Road
North Ryde
NSW 2113
Australia

This leaflet was prepared in December 2023