Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about EDECRIN. It does not contain all the available information.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking EDECRIN against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
What EDECRIN is used for
EDECRIN helps to reduce the amount of fluid in the body for people who have:
- swelling of the ankles, feet and legs, which is called oedema
- fluid accumulation in the lungs, which is called pulmonary oedema
- fluid accumulation in the stomach area (which is also called ascites) due to liver disease
EDECRIN is also used in children, over 2 years old, to remove fluid that occurs in some heart and kidney conditions.
EDECRIN belongs to a group of medicines called diuretics or fluid tablets. They work by making your kidneys pass more water and salt from the body. This helps to reduce swelling caused by fluid.
Your doctor may have prescribed EDECRIN for another reason. Ask your doctor if you have any questions about why EDECRIN has been prescribed for you.
EDECRIN is not addictive.
Before you take EDECRIN
When you must not take it
Do not take EDECRIN if:
- you have an allergy to EDECR1N or any of the ingredients listed at the end of this leafIet
- you are pregnant or intend to become pregnant
Like most medicines, EDECRIN is not recommended for use during pregnancy.
- you are not passing urine
- the bottle shows signs of tampering
- the expiry date on the pack has passed.
If you take this medicine after the expiry date has passed, it may not work.
If you are not sure whether you should start taking EDECRIN, talk to your doctor.
Do not give EDECRIN to infants under two years of age.
Before you start to take it
Your doctor must know about all the following before you start to take EDECRIN.
- if you are breast feeding or plan to breast feed.
Like most medicines, EDECRIN is not recommended for use while breast feeding. If it is necessary for you to take EDECRIN, your doctor may ask you to stop breast feeding.
- if you have any medical conditions, especially the following:
- liver disease
- heart disease
- if you have any allergies to any other medicines or any other substances, such as foods, preservatives or dyes.
If you have not told your doctor about any of the above, tell them before you take any EDECRIN.
Taking other medicines
Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines and EDECRIN may interfere with each other. These include:
- medicines used to treat high blood pressure
- certain antibiotics such as aminoglycosides
- warfarin, a medicine used to prevent blood clots
- lithium, a medicine used to treat severe mood swings
- corticosteroids, such as prednisone and cortisone
These medicines may be affected by EDECRIN, or may affect how well it works. You may need different amounts of your medicine, or you may need to take different medicines.
Your doctor or pharmacist has more information on medicines to avoid while taking EDECRIN.
How to take EDECRIN
How much to take
Take EDECRIN only when prescribed by your doctor.
Your doctor will tell you how many tablets you need to take each day. This depends on your condition and whether you are taking other medicines.
For adults, the usual starting dose is two 25 mg tablets taken once a day. Depending on your response, your doctor may increase this dose. Most people take between 50 mg and 150 mg per day, which is 2 to 6 tablets per day. If you are taking more than two tablets per day, your dose will be divided into two doses per day.
For children over 2 years of age, the usual starting dose is 25 mg (1 tablet) taken once a day.
Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the bottle, ask your doctor or pharmacist for help.
Swallow EDECRIN with a glass of water.
When to take it
If you take EDECRIN once a day, take it immediately after breakfast.
If you take EDECRIN more than once a day, take your first dose immediately after breakfast and take your last dose no later than 6 p.m., unless your doctor tells you otherwise. EDECRIN may increase the amount of water (urine) you pass and also the number of times you go to the toilet. By taking the last dose no later than 6 p.m., there may be less chance of your sleep being disturbed.
Follow the above instructions even if you don't take EDECRIN every day.
Your doctor will determine whether or not you need to take EDECRIN everyday.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your tablet(s) as you would normally.
If you are not sure whether to skip the dose, talk to your doctor or pharmacist.
Do not take a double dose to make up for the dose that you missed.
If you have trouble remembering to take your tablets, ask your pharmacist for some hints.
If you take too much (overdose)
Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, or go to accident and emergency at your nearest hospital, if you think that you or anyone else may have taken too much EDECRIN. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too many tablets, you will probably feel light-headed, dizzy, or weak, or you may faint. You may also become very thirsty, confused, have a change in the amount of urine passed, have a fast heart beat, have muscle cramps, or feel a tingling sensation of the skin.
While you are using EDECRIN
Things you must do
If you become pregnant while taking EDECRIN tell your doctor immediately.
Have your blood tested when your doctor says to make sure your potassium and some other substances in the blood known as electrolytes are at the right level.
EDECRIN may cause a loss of water, potassium and some other electrolytes from your body. This may cause:
- dry mouth or thirst
- weakness, tiredness, numbness tingling in the hands and/or feet
- muscle pains or cramps
- irregular or fast heart beat
- passing less urine than normal.
Tell your doctor if you get any of these symptoms.
Your doctor may ask you to take a potassium supplement white taking EDECRIN.
If you are about to be started on any new medicine tell your doctor and pharmacist that you are taking EDECRIN.
If you plan to have surgery (even at the dentist) that needs a general anaesthetic, tell your doctor or dentist that you are taking EDECRIN. Your blood pressure may drop suddenly.
Things you must not do
Do not give EDECRIN to anyone else, even if they have the same condition as you.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking EDECRIN. EDECRIN helps most people with some types of fluid accumulation but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
- feeling sick (which is also called nausea), vomiting, loss of appetite
- generally feeling unwell
- headache, tiredness, weakness
- stomach upset or pain, diarrhoea
- dry mouth or thirst
- muscle pains or cramps
- passing less urine than normal
- ringing in the ears
- blurred vision
These are usually mild effects of EDECRIN, but may be serious.
Tell your doctor immediately if you notice any of the following:
- irregular or fast heart beat
- yellowing of the skin and eyes, which is also called jaundice
- difficulty in swallowing
- signs of frequent or worrying infections such as fever, severe chills, sore throat or mouth ulcers
- bruising more easily than normal
- spinning sensation, which is also called vertigo
- numbness or tingling in the hands and/or feet
- feeling anxious or confused
- skin rash
- blood in the urine
These may be serious side effects. You may need urgent medical attention. Serious side effects are rare.
Tell your doctor immediately or go to casualty at your nearest hospital if you notice any of the following:
- vomiting blood or material that looks like coffee grounds
- bleeding from the back passage, black, sticky bowel motions (stools) or bloody diarrhoea
- severe pain or tenderness in any part of the stomach
- seizures or fits
These are very serious side effects. You may need urgent medical attention. These side effects are rare.
Other side effects not listed above may also occur in some patients. Tell your doctor if you notice any other effects.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
After using EDECRIN
Keep your tablets in the bottle until it is time to take them. If you take the tablets out of the bottle they may not keep well.
Keep EDECRIN in a cool dry place where the temperature stays below 25 degrees C. Do not store it or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills. Heat and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking the tablets, or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
What it looks like
EDECRIN is a white capsule-shaped tablet, scored and embossed VRX 205 on one side, other side embossed EDECRIN.
A bottle contains 100 tablets.
EDECRIN contains ethacrynic acid 25 mg per tablet.
- magnesium stearate
- silica colloidal anhydrous
- maize starch
- purified talc
EDECRIN does nut contain gluten, sucrose, tartrazine or any other azo dyes.
EDECRIN is supplied in Australia by:
Invida Australia Pty Ltd
A.B.N. 62 116 935 758
Level 8/67 Albert Avenue
CHATSWOOD, NSW 2067
This leaflet was prepared in August 2012.
Australian Register Number:
AUST R 96871
* Registered Trademark of Valeant Pharmaceuticals
North America, Bridgewater, N.J., U.S.A.
Published by MIMS November 2014